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BDBM108009 US8604218, 2.023

SMILES: C(N1CC[C@@H](C1)Nc1cccc2cnccc12)c1cccc(c1)C1CC1

InChI Key: InChIKey=ZOHRKOKZKGNCNH-RNZRUAGMNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108009   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM108009
PNG
(US8604218, 2.023)
Show SMILES C(N1CC[C@@H](C1)Nc1cccc2cnccc12)c1cccc(c1)C1CC1
Show InChI InChI=1/C23H25N3/c1-3-17(13-19(4-1)18-7-8-18)15-26-12-10-21(16-26)25-23-6-2-5-20-14-24-11-9-22(20)23/h1-6,9,11,13-14,18,21,25H,7-8,10,12,15-16H2/t21-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.57E+4n/an/an/an/a7.2n/a



Inspire Pharmaceuticals, Inc.

US Patent


Assay Description
Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...


US Patent US8604218 (2013)


BindingDB Entry DOI: 10.7270/Q2319TJD
More data for this
Ligand-Target Pair