BDBM108055 4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) amino)pyrimidin-2-yl)amino)-N-(4,6- dimethylpyrimidin-2-yl)benzenesulfonamide (P2e)

SMILES CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(cc2)S(=O)(=O)Nc2nc(C)cc(C)n2)n1

InChI Key InChIKey=MGSXHFUDTNNPGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108055   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Shandong Institute Of Pharmaceutical Industry

LigandPNGBDBM108055(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50:  22nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shandong Institute Of Pharmaceutical Industry

LigandPNGBDBM108055(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50:  12nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed