BDBM108058 N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- 6-yl)amino)pyrimidin-2-yl)amino) benzenesulfonamide (P1g)

SMILES Cc1n(C)nc2cc(Nc3ccnc(Nc4ccc(cc4)S(=O)(=O)NC(N)=N)n3)ccc12

InChI Key InChIKey=DUFZPHYLPIPJCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108058   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Shandong Institute Of Pharmaceutical Industry

LigandPNGBDBM108058(N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- ...)
Affinity DataIC50:  930nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shandong Institute Of Pharmaceutical Industry

LigandPNGBDBM108058(N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- ...)
Affinity DataIC50:  1.34E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed