BDBM108211 US8598157, I-88

SMILES COc1ncc(cc1NS(=O)(=O)c1cnn(C)c1)C#Cc1c(C)ncnc1N1CCOCC1

InChI Key InChIKey=OQRHMXNCZXADGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108211   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM108211(US8598157, I-88)
Affinity DataIC50:  0.550nMT: 2°CAssay Description:This PI3Kalpha assay provides an IC50 value indicative of the activity of the compounds to inhibit PI3 kinase alpha activity. Inhibition of PI3 kinas...More data for this Ligand-Target Pair
In DepthDetails US Patent