BDBM10859 4-methylbenzene-1-sulfonamide::CHEMBL574::aromatic/heteroaromatic sulfonamide 4::hCA inhibitor, 7

SMILES: Cc1ccc(cc1)S(=O)(=O)N

InChI Key: InChIKey=LMYRWZFENFIFIT-UHFFFAOYSA-N

Data: 89 KI  5 IC50  4 Kd  2 K_off

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 100 hits for monomerid = 10859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.32E+5	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.93E+5	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	715	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Bovine)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Bovine)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase 7 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase, alpha family (Thiomicrospira crunogena (strain XCL-2))	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	-8.85	n/a	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Delta carbonic anhydrase (Thalassiosira weissflogii)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		424	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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CARBONIC ANHYDRASE (Helicobacter pylori (strain J99 / ATCC 700824) (Ca...)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM10859 (CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...) Show SMILES Show InChI	GoogleScholar	UniChem		460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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