BDBM10881 CHEMBL288100::MZA3::Methazolamide::Methazolamide (MZA)::Methazolamide, MZA::N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide::Sulfonamide, 2::cid_4100::sulfonamide 2

SMILES: CC(=O)/N=C\1/N(N=C(S1)S(=O)(=O)N)C

InChI Key: InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N

Data: 290 KI  9 IC50  2 EC50

PDB links: 7 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 300 hits for monomerid = 10881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	40	n/a	n/a	n/a	n/a
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Corticotropin-releasing factor-binding protein (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Bovine)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	-11.8	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
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Carbonic anhydrase 7 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	-10.6	n/a	n/a	n/a	n/a	n/a	7.5	22
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Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	-10.7	n/a	n/a	n/a	n/a	n/a	7.5	25
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Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10881 (CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		14	-10.7	n/a	n/a	n/a	n/a	n/a	7.4	25
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