BDBM10887 Sulfamate 7::Topiramate (TPM)::US11535599, Example topiramate::[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate

SMILES: CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

InChI Key: InChIKey=KJADKKWYZYXHBB-UHFFFAOYSA-N

Data: 291 KI  12 IC50  4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 307 hits for monomerid = 10887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Bovine)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Rat)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	25.4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	13.8	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	290	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rat)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10887 (Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		5	-11.2	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair