BDBM10888 1,2-benzoxazol-3-ylmethanesulfonamide::CHEMBL750::SPR_2::US10172837, Zonisamide::Zonisamide::Zonisamide (ZNA)::Zonisamide (ZNS)::Zonisamide, 1::Zonisamide, ZNS

SMILES: c1ccc2c(c1)c(no2)CS(=O)(=O)N

InChI Key: InChIKey=UBQNRHZMVUUOMG-UHFFFAOYSA-N

Data: 143 KI  2 IC50  3 Kd  1 K_off  1 K_on

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 148 hits for monomerid = 10888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Bovine)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.26E+3	n/a	1.43E+5	0.611	7.4	25
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Carbonic anhydrase 2 (Bovine)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20.6	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	47.6	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	-11.1	n/a	n/a	n/a	n/a	n/a	7.5	20
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		20	-10.3	n/a	n/a	n/a	n/a	n/a	7.5	20
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	-10.2	n/a	n/a	n/a	n/a	n/a	7.4	25
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	-9.99	n/a	n/a	n/a	n/a	n/a	7.5	20
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		35.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		41	-10.1	n/a	n/a	n/a	n/a	n/a	7.5	25
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Carbonic anhydrase 1 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM10888 (Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...) Show SMILES Show InChI	GoogleScholar	UniChem		56	-9.72	n/a	n/a	n/a	n/a	n/a	7.5	20
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