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BDBM109467 US9695170 142

SMILES: CC(CC(O)=O)NC(=O)c1ncc2n(Cc3ccccc3)c(=O)c(Cc3ccccc3)cc2c1O

InChI Key: InChIKey=XNDCICQSEXEUGM-UHFFFAOYNA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109467   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIF-PH2


(Homo sapiens (Human))
BDBM109467
PNG
(US9695170 142)
Show SMILES CC(CC(O)=O)NC(=O)c1ncc2n(Cc3ccccc3)c(=O)c(Cc3ccccc3)cc2c1O
Show InChI InChI=1/C27H25N3O5/c1-17(12-23(31)32)29-26(34)24-25(33)21-14-20(13-18-8-4-2-5-9-18)27(35)30(22(21)15-28-24)16-19-10-6-3-7-11-19/h2-11,14-15,17,33H,12-13,16H2,1H3,(H,29,34)(H,31,32)
PDB
MMDB

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PC cid
PC sid
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Similars

US Patent
n/an/a 8.79E+4n/an/an/an/a7.4n/a



FibroGen Inc

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9695170 (2017)


BindingDB Entry DOI: 10.7270/Q2P55KN0
More data for this
Ligand-Target Pair