BDBM11034 1-pentafluorophenylamido-5-sulfonamidoindane::2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)benzamide::CHEMBL205867::Indanesulfonamide Derivative 11c

SMILES NS(=O)(=O)c1ccc2C(CCc2c1)NC(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key InChIKey=GSDOCCQCQXIOCL-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11034   

TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11034(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human carbonic anhydrase 7 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Medical University Of Gdansk

Curated by ChEMBL
LigandPNGBDBM11034(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of CA9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Medical University Of Gdansk

Curated by ChEMBL
LigandPNGBDBM11034(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Affinity DataKi:  3.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11034(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11034(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM11034(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Affinity DataKi:  490nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM11034(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Affinity DataKi:  770nM ΔG°:  -8.25kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed