BDBM11053 CHEMBL386049::N-(4-sulfamoylphenyl)-2-sulfanylbenzamide::reduced monomeric thio of compound 5a::reduced thio H5a

SMILES NS(=O)(=O)c1ccc(NC(=O)c2ccccc2S)cc1

InChI Key InChIKey=MRLVIVXGUGNENL-UHFFFAOYSA-N

Data  10 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 11053   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  9.10nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  16nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  16nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow techniqueMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  79nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  114nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  276nM ΔG°:  -8.85kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11053(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Affinity DataKi:  276nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed