BDBM110552 US8614234, 20::US9725433, 20

SMILES COC(=O)c1c[nH]c(c1)-c1cc(Oc2cccc(c2)C(=O)Nc2cc(C)ccc2F)ccn1

InChI Key InChIKey=NKTLRPAMUNWXJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110552   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM110552(US8614234, 20 | US9725433, 20)
Affinity DataIC50:  28nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM110552(US8614234, 20 | US9725433, 20)
Affinity DataIC50:  28nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
In DepthDetails US Patent