BDBM110706 US8614206, 139

SMILES: Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@H](N)[C@H](F)CC1

InChI Key: InChIKey=NHXVGMQFCYBLTL-UHFFFAOYSA-N

Data: 5 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 110706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 4 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-3 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		0.0400	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
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Serine/threonine-protein kinase pim-2 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM110706 (US8614206, 139) Show SMILES Show InChI	GoogleScholar	UniChem		1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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