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BDBM110732 US8614206, 258

SMILES: Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CCCC(C1)C(F)(F)F

InChI Key: InChIKey=GATKXKCLQKNCTC-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 110732   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM110732
PNG
(US8614206, 258)
Show SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CCCC(C1)C(F)(F)F
Show InChI InChI=1/C20H19F5N6OS/c1-30-19(31-7-3-4-10(9-31)20(23,24)25)13(8-27-30)28-17(32)15-16(26)33-18(29-15)14-11(21)5-2-6-12(14)22/h2,5-6,8,10H,3-4,7,9,26H2,1H3,(H,28,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.353n/an/an/an/an/an/a7.2n/a



F. Hoffmann-La Roche Inc

US Patent


Assay Description
PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...


US Patent US8614206 (2013)


BindingDB Entry DOI: 10.7270/Q2W66JFG
More data for this
Ligand-Target Pair