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BDBM110842 US8614206, 393

SMILES: Cn1ncc(NC(=O)c2nc(sc2N)-c2cccc(=O)[nH]2)c1N1CCC[C@H](N)CC1

InChI Key: InChIKey=FCFASDMKPQXXIJ-LDGXTIHJNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 110842   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM110842
PNG
(US8614206, 393)
Show SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2cccc(=O)[nH]2)c1N1CCC[C@H](N)CC1
Show InChI InChI=1/C19H24N8O2S/c1-26-19(27-8-3-4-11(20)7-9-27)13(10-22-26)24-17(29)15-16(21)30-18(25-15)12-5-2-6-14(28)23-12/h2,5-6,10-11H,3-4,7-9,20-21H2,1H3,(H,23,28)(H,24,29)/t11-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
14n/an/an/an/an/an/a7.2n/a



F. Hoffmann-La Roche Inc

US Patent


Assay Description
PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...


US Patent US8614206 (2013)


BindingDB Entry DOI: 10.7270/Q2W66JFG
More data for this
Ligand-Target Pair