BDBM110961 US8614206, 518

SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@](C)(N)CC(F)(F)C1

InChI Key InChIKey=YLJCMWKIAARCQT-HXUWFJFHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 110961   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110961(US8614206, 518)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of recombinant human PIM1 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110961(US8614206, 518)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of recombinant human PIM3 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110961(US8614206, 518)
Affinity DataKi:  5nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In DepthDetails US Patent