BDBM111169 US10556908, Example 21::US9695180, 21

SMILES CN(C)[C@@H]1CCN(C1)C(=O)N(C)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(C)cc2)n2ccnc12

InChI Key InChIKey=XQBFHKCPYTZSGL-HSZRJFAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 111169   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM111169(US10556908, Example 21 | US9695180, 21)
Affinity DataIC50:  275nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A [151-852](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM111169(US10556908, Example 21 | US9695180, 21)
Affinity DataIC50:  275nMpH: 7.5 T: 2°CAssay Description:10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM NaCl, 5 mM DTT) were preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent