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BDBM112068 US8623889, 66

SMILES: CC(C)C(=O)Nc1cc2ccc(cc2cn1)-c1cc(F)ccc1C

InChI Key: InChIKey=CWTANYORWHRSCW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112068   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM112068
PNG
(US8623889, 66)
Show SMILES CC(C)C(=O)Nc1cc2ccc(cc2cn1)-c1cc(F)ccc1C
Show InChI InChI=1S/C20H19FN2O/c1-12(2)20(24)23-19-9-14-5-6-15(8-16(14)11-22-19)18-10-17(21)7-4-13(18)3/h4-12H,1-3H3,(H,22,23,24)
PDB
MMDB

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Similars

US Patent
9n/an/an/an/an/an/an/an/a



Genentech Inc

US Patent


Assay Description
Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...


US Patent US8623889 (2014)


BindingDB Entry DOI: 10.7270/Q2JQ0ZNX
More data for this
Ligand-Target Pair