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BDBM112228 US8623889, 226

SMILES: CC(C)S(=O)(=O)c1ccc2cc(NC(=O)C3CC3)ncc2c1

InChI Key: InChIKey=KSAMDFSXJGHOJC-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112228   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM112228
PNG
(US8623889, 226)
Show SMILES CC(C)S(=O)(=O)c1ccc2cc(NC(=O)C3CC3)ncc2c1
Show InChI InChI=1S/C16H18N2O3S/c1-10(2)22(20,21)14-6-5-12-8-15(17-9-13(12)7-14)18-16(19)11-3-4-11/h5-11H,3-4H2,1-2H3,(H,17,18,19)
PDB
MMDB

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Similars

US Patent
1n/an/an/an/an/an/an/an/a



Genentech Inc

US Patent


Assay Description
Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...


US Patent US8623889 (2014)


BindingDB Entry DOI: 10.7270/Q2JQ0ZNX
More data for this
Ligand-Target Pair