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BDBM112386 US8623889, 385

SMILES: O=C(Nc1cc2ccc(cc2cn1)-c1ccncc1)C1CC1

InChI Key: InChIKey=ULAQIRXCYKFERG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112386   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM112386
PNG
(US8623889, 385)
Show SMILES O=C(Nc1cc2ccc(cc2cn1)-c1ccncc1)C1CC1
Show InChI InChI=1S/C18H15N3O/c22-18(13-1-2-13)21-17-10-15-4-3-14(9-16(15)11-20-17)12-5-7-19-8-6-12/h3-11,13H,1-2H2,(H,20,21,22)
PDB
MMDB

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PC sid
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Similars

US Patent
5.65n/an/an/an/an/an/an/an/a



Genentech Inc

US Patent


Assay Description
Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...


US Patent US8623889 (2014)


BindingDB Entry DOI: 10.7270/Q2JQ0ZNX
More data for this
Ligand-Target Pair