BDBM112415 US8623889, 414

SMILES Cc1c(F)cncc1-c1cc2cnc(NC(=O)[C@@H]3C[C@@H]3F)cc2cn1

InChI Key InChIKey=RPLFEMGECJQJCF-OCCSQVGLSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112415   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112415(US8623889, 414)
Affinity DataKi:  0.168nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent