BDBM112738 US8629141, 5

SMILES O[C@H]1CCC(CC1)NC(=O)[C@@H]1NC[C@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21

InChI Key InChIKey=QTYORMVOOUGMHF-UWBQXDLGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112738   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112738(US8629141, 5)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent