BDBM113591 US8633196, 23::US9365529, 23

SMILES CC(C)C(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO

InChI Key InChIKey=NVPQXUAYORUQIU-SANMLTNESA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 113591   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM113591(US8633196, 23 | US9365529, 23)
Affinity DataIC50:  53nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM113591(US8633196, 23 | US9365529, 23)
Affinity DataIC50:  53nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterstitial collagenase(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113591(US8633196, 23 | US9365529, 23)
Affinity DataIC50:  2.22E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113591(US8633196, 23 | US9365529, 23)
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113591(US8633196, 23 | US9365529, 23)
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113591(US8633196, 23 | US9365529, 23)
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-1(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113591(US8633196, 23 | US9365529, 23)
Affinity DataIC50:  1.07E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent