BDBM11399 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 9::3-[[N-(2-Methoxyethyl)-N-(2-propenyl)amino]methyl]-2-methyl-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride::3-{[(2-methoxyethyl)(prop-2-en-1-yl)amino]methyl}-2-methyl-1,1-dioxo-2H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide hydrochloride::Compound 17a7

SMILES COCCN(CC=C)CC1=Cc2cc(sc2S(=O)(=O)N1C)S(N)(=O)=O

InChI Key InChIKey=NKKBOUBMVAAJAF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11399   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11399(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)
Affinity DataKi:  0.100nM ΔG°:  -14.2kcal/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11399(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)
Affinity DataIC50:  16.9nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11399(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)
Affinity DataIC50:  1.11nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed