BDBM1152 (4R,5S,6R,7R)-1,3-diaza-1-[(3-cyanophenyl)methyl]-4,7-bis-(phenylmethyl)-5-(hydroxy)-bicyclo[4.1.0]heptan-2-one::3-{[(4R,5S,6R)-4,7-dibenzyl-5-hydroxy-2-oxo-1,3-diazabicyclo[4.1.0]heptan-3-yl]methyl}benzonitrile::Tetrahydropyrimidinone deriv. 100

SMILES [H][C@]12C(Cc3ccccc3)N1C(=O)N(Cc1cccc(c1)C#N)[C@H](Cc1ccccc1)[C@@H]2O

InChI Key InChIKey=KOIYMMLMGFDEHH-KJGTZIPBSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1152   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM1152((4R,5S,6R,7R)-1,3-diaza-1-[(3-cyanophenyl)methyl]-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM1152((4R,5S,6R,7R)-1,3-diaza-1-[(3-cyanophenyl)methyl]-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed