BDBM1152 (4R,5S,6R,7R)-1,3-diaza-1-[(3-cyanophenyl)methyl]-4,7-bis-(phenylmethyl)-5-(hydroxy)-bicyclo[4.1.0]heptan-2-one::3-{[(4R,5S,6R)-4,7-dibenzyl-5-hydroxy-2-oxo-1,3-diazabicyclo[4.1.0]heptan-3-yl]methyl}benzonitrile::Tetrahydropyrimidinone deriv. 100
SMILES [H][C@]12C(Cc3ccccc3)N1C(=O)N(Cc1cccc(c1)C#N)[C@H](Cc1ccccc1)[C@@H]2O
InChI Key InChIKey=KOIYMMLMGFDEHH-KJGTZIPBSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 1152
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair