BDBM11627 β-CA inhibitor, 3::2-N-(4-amino-3-fluoro-5-iodobenzene)-1,3,4-thiadiazole-2,5-disulfonamide::5-{[(4-amino-3-fluoro-5-iodophenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide::aminobenzolamide 20

SMILES Nc1c(F)cc(cc1I)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=YMECUEKBIBTNRW-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11627   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11627(β-CA inhibitor, 3 | 2-N-(4-amino-3-fluoro-5-i...)
Affinity DataKi:  0.300nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11627(β-CA inhibitor, 3 | 2-N-(4-amino-3-fluoro-5-i...)
Affinity DataKi:  1.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11627(β-CA inhibitor, 3 | 2-N-(4-amino-3-fluoro-5-i...)
Affinity DataKi:  2.10nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11627(β-CA inhibitor, 3 | 2-N-(4-amino-3-fluoro-5-i...)
Affinity DataKi:  21nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11627(β-CA inhibitor, 3 | 2-N-(4-amino-3-fluoro-5-i...)
Affinity DataKi:  120nM ΔG°:  -9.43kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11627(β-CA inhibitor, 3 | 2-N-(4-amino-3-fluoro-5-i...)
Affinity DataKi:  300nM ΔG°:  -8.89kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11627(β-CA inhibitor, 3 | 2-N-(4-amino-3-fluoro-5-i...)
Affinity DataKi:  410nM ΔG°:  -8.71kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed