BDBM117005 US8637532, 732

SMILES NC(=O)c1cc(cc2c(NC3CCCNC3)ncnc12)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ASDFZNDXNNEZEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 117005   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM117005(US8637532, 732)
Affinity DataIC50: 520nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed as 384-well Flashplate assay (PerkinElmer LAS Germany GmbH). 3.4 nM His6-PDK1(Delta 1-50) (PDK1 that has a His-tag cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM117005(US8637532, 732)
Affinity DataIC50: 975nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent