BDBM117567 US8653087, III-247

SMILES CN(C)c1cccc(NC(=O)c2ccc(C)c(Nc3ncnc4cnc(nc34)N3CCCCC3)c2)c1

InChI Key InChIKey=HQKYQGZIDPMCBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 117567   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117567(US8653087, III-247)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent