BDBM11870 4-{[4-(4-Chlorophenoxy)phenyl]sulfonyl}-N-hydroxy tetrahydro-2H-pyran-4-carboxamide::4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxyoxane-4-carboxamide::alpha-sulfone 21

SMILES: ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1

InChI Key: InChIKey=HBYRXCFAHCMHAA-UHFFFAOYSA-N

Data: 11 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 11870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	435	n/a	n/a	n/a	n/a	n/a	n/a
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Collagenase 3 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
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Stromelysin-1 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil collagenase (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-14 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-9 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Collagenase 3 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-9 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Collagenase 3 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-9 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Stromelysin-1 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Stromelysin-1 (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		18.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Interstitial collagenase (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		435	-8.67	n/a	n/a	n/a	n/a	n/a	7.5	25
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Interstitial collagenase (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Matrilysin (Human)	BDBM11870 (4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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