BDBM118883 US8674113, 140

SMILES Cn1c(Nc2c(Cl)ccc(CNC(=O)C(C)(C)F)c2Cl)nc2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c(cc12)N1CCC(F)(F)CC1

InChI Key InChIKey=VBWLKINPARVGLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118883   

TargetProstaglandin E synthase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM118883(US8674113, 140)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:The aim of this assay is to determine the affinity of a test compound for the mPGES-1 enzyme. 47 μl of recombinant human mPGES-1 (0.5 μg p...More data for this Ligand-Target Pair
In DepthDetails US Patent