BDBM119125 GS4

SMILES CC(C)[C@H](NC(=O)N(C)Cc1csc(n1)C(C)C)C(=O)NCCCCNC(=O)OCc1cncs1

InChI Key InChIKey=OWSUPSVMUSHQHC-IBGZPJMESA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 119125   

TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM119125(GS4)
Affinity DataIC50:  1.50E+4nMAssay Description:The inhibitory potency of compounds GS4-GS8 on the 7-benzyloxy-4-(trifluoromethyl)coumarin hydroxylase activity of CYP3A4 was evaluated according to ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM119125(GS4)
Affinity DataKd:  1.31E+4nMpH: 7.4Assay Description:Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM119125(GS4)
Affinity DataKd:  1.50E+3nMpH: 7.4Assay Description:Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots...More data for this Ligand-Target Pair