BDBM119126 GS5

SMILES C[C@@H](CC[C@H](C)NC(=O)[C@@H](NC(=O)N(C)Cc1csc(n1)C(C)C)C(C)C)NC(=O)OCc1cncs1

InChI Key InChIKey=TYLOVNGZCFIJOG-WFXMLNOXSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 119126   

TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM119126(GS5)
Affinity DataIC50:  1.00E+4nMAssay Description:The inhibitory potency of compounds GS4-GS8 on the 7-benzyloxy-4-(trifluoromethyl)coumarin hydroxylase activity of CYP3A4 was evaluated according to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM119126(GS5)
Affinity DataKd:  7.30E+3nMpH: 7.4Assay Description:Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM119126(GS5)
Affinity DataKd:  400nMpH: 7.4Assay Description:Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed