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BDBM119478 US8680120, 25-37

SMILES: COc1cc2cc(-c3ccoc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl

InChI Key: InChIKey=CLYDIMUKBUEGRQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119478   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid EP1 receptor


(Rattus norvegicus (Rat))
BDBM119478
PNG
(US8680120, 25-37)
Show SMILES COc1cc2cc(-c3ccoc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl
Show InChI InChI=1S/C20H15ClN2O4/c1-26-19-8-13-7-17(12-5-6-27-11-12)23(18(13)9-15(19)21)10-14-3-2-4-16(22-14)20(24)25/h2-9,11H,10H2,1H3,(H,24,25)
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PC sid
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Similars

US Patent
n/an/a 27n/an/an/an/an/an/a



Kissei Pharmaceutical Co., Ltd.

US Patent


Assay Description
The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...


US Patent US8680120 (2014)


BindingDB Entry DOI: 10.7270/Q2183554
More data for this
Ligand-Target Pair