BDBM120095 US10525036, Example GDC-0994::US10934304, Example GDC-0994::US8697715, 39::US9259470, 39

SMILES: Cn1c(ccn1)Nc2nccc(n2)C3=CC(=O)N(C=C3)[C@H](CO)c4ccc(c(c4)F)Cl

InChI Key: InChIKey=RZUOCXOYPYGSKL-UHFFFAOYSA-N

Data: 17 IC50  5 Kd

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 120095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mitogen-activated protein kinase 3 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 6 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.3	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1/3 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1/3 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM120095 (US8697715, 39 | US9259470, 39 | US10525036, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.3	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair