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BDBM120368 US8703807, 4

SMILES: CC(C)Oc1ccc(cc1)N1CC[C@]2(CC[C@@](O)(CN3CCCCC3=O)CC2)C1=O

InChI Key: InChIKey=MZTCLPDWZWEGMR-PSWAGMNNSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120368   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM120368
PNG
(US8703807, 4)
Show SMILES CC(C)Oc1ccc(cc1)N1CC[C@]2(CC[C@@](O)(CN3CCCCC3=O)CC2)C1=O
Show InChI InChI=1S/C24H34N2O4/c1-18(2)30-20-8-6-19(7-9-20)26-16-14-23(22(26)28)10-12-24(29,13-11-23)17-25-15-4-3-5-21(25)27/h6-9,18,29H,3-5,10-17H2,1-2H3/t23-,24+
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KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 27.4n/an/an/an/a7.24



Hoffmann-La Roche Inc

US Patent


Assay Description
HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...


US Patent US8703807 (2014)


BindingDB Entry DOI: 10.7270/Q2RN36HB
More data for this
Ligand-Target Pair