BDBM12042 (2R,3R)-3-{[(1S)-1-[(4-carbamimidamidobutyl)carbamoyl]-3-methylbutyl]carbamoyl}oxirane-2-carboxylic acid::E-64::L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatine::N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE::trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane

SMILES: [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H]-1-[#8]-[#6@H]-1-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7]

InChI Key: InChIKey=VHDAHAMWVNXMSP-UHFFFAOYSA-N

Data: 1 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 12042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Falcipain-2 (malaria parasite P. falciparum)	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	5.5	22
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Cysteine proteinase falcipain 2a (malaria parasite P. falciparum)	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cysteine proteinase falcipain 3 (Plasmodium falciparum (isolate 3D7))	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
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Falcipain 2 (malaria parasite P. falciparum)	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
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Cruzipain (Trypanosoma cruzi)	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cruzipain (Trypanosoma cruzi)	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin K (Human)	BDBM12042 (L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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