BDBM120516 US8703768, 116::US8703768, 148

SMILES CNC(=O)c1c(NC(=O)c2nc(cnc2Nc2cncnc2)C2CC2)cnn1C

InChI Key InChIKey=WCFFGYGVMUTILN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120516   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120516(US8703768, 116 | US8703768, 148)
Affinity DataIC50:  14.4nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120516(US8703768, 116 | US8703768, 148)
Affinity DataIC50:  4.5nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair