BDBM12079 6-Chloro-4-cyclohexyloxy-3-isopropylquinol-2-one::6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dihydroquinolin-2-one::quinolone-based inhibitor 2b

SMILES: CC(C)C1=C(c2cc(ccc2NC1=O)Cl)OC3CCCCC3

InChI Key: InChIKey=OQCFORGSZJSAEL-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM12079 (6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dih...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	630	n/a	n/a	n/a	n/a	7.8	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1)	BDBM12079 (6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dih...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.8	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I] (Human immunodeficiency virus type 1)	BDBM12079 (6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dih...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	7.8	22
TBA									Citation and Details
					More data for this Ligand-Target Pair