BDBM120816 (Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-morpholinopropoxy) quinolin-4-yl)oxy)phenyl)amino)methylene)-3-methyl-1-(2- (trifluoromethyl)phenyl)-1H-pyrazol-5(4H)-one (17)
SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCOCC1
InChI Key InChIKey=KEDANNMRCOENMZ-LLJCYPMUSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 120816
Affinity DataIC50: 2.20nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit [1-973](Homo sapiens (Human))
Shenyang Pharmaceutical University
Shenyang Pharmaceutical University
Affinity DataIC50: 2.30nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Shenyang Pharmaceutical University
Shenyang Pharmaceutical University
Affinity DataIC50: 8.38nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Shenyang Pharmaceutical University
Shenyang Pharmaceutical University
Affinity DataIC50: 8.56nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University
Shenyang Pharmaceutical University
Affinity DataIC50: 326nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Shenyang Pharmaceutical University
Shenyang Pharmaceutical University
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Shenyang Pharmaceutical University
Affinity DataIC50: 4.24nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha [1-973](Homo sapiens (Human))
Shenyang Pharmaceutical University
Shenyang Pharmaceutical University
Affinity DataIC50: 32.2nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair