BDBM12082 ((2-chloro-5-methyl-phenyl)-{6-[4-(3-(dimethylamino)-2-hydroxy-propoxy)-phenylamino]-pyrimidin-4-yl}-amino)-acetonitrile::2-[(2-chloro-5-methylphenyl)[6-({4-[(2R)-3-(dimethylamino)-2-hydroxypropoxy]phenyl}amino)pyrimidin-4-yl]amino]acetonitrile::AZ2

SMILES: CN(C)C[C@@H](O)COc1ccc(Nc2cc(ncn2)N(CC#N)c2cc(C)ccc2Cl)cc1

InChI Key: InChIKey=FIRZNFNHYVXQPP-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 12082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Human)	BDBM12082 (2-[(2-chloro-5-methylphenyl)[6-({4-[(2R)-3-(dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	7.5	30
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Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 [K89T] (Human)	BDBM12082 (2-[(2-chloro-5-methylphenyl)[6-({4-[(2R)-3-(dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	7.5	30
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					More data for this Ligand-Target Pair
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D] (Human)	BDBM12082 (2-[(2-chloro-5-methylphenyl)[6-({4-[(2R)-3-(dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	7.5	30
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					More data for this Ligand-Target Pair
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D,K98T] (Human)	BDBM12082 (2-[(2-chloro-5-methylphenyl)[6-({4-[(2R)-3-(dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	640	n/a	n/a	n/a	n/a	7.5	30
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM12082 (2-[(2-chloro-5-methylphenyl)[6-({4-[(2R)-3-(dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair