BDBM12086 3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 4::N-{5-acetyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl}-4-methoxybenzamide

SMILES COc1ccc(cc1)C(=O)Nc1[nH]nc2CN(Cc12)C(C)=O

InChI Key InChIKey=WKUZSVHNZTYTJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12086   

TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12086(3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 4...)
Affinity DataIC50:  660nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12086(3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 4...)
Affinity DataIC50:  1.37E+3nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed