BDBM12107 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 15::4-(4-Methyl-piperazin-1-yl)-N-[5-(2-thiophen-2-yl-acetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-benzamide::4-(4-methylpiperazin-1-yl)-N-{5-[2-(thiophen-2-yl)acetyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl}benzamide::5-Amido-pyrrolopyrazole 3::CHEMBL516110

SMILES: CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1[nH]nc2CN(Cc12)C(=O)Cc1cccs1

InChI Key: InChIKey=BMCKWRUTJXVUFF-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 12107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Human)	BDBM12107 (CHEMBL516110 | 5-Amido-pyrrolopyrazole 3 | 4-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	7.5	22
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Aurora kinase A (Human)	BDBM12107 (CHEMBL516110 | 5-Amido-pyrrolopyrazole 3 | 4-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	7.5	22
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Serine/threonine-protein kinase PLK1 (Human)	BDBM12107 (CHEMBL516110 | 5-Amido-pyrrolopyrazole 3 | 4-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM12107 (CHEMBL516110 | 5-Amido-pyrrolopyrazole 3 | 4-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM12107 (CHEMBL516110 | 5-Amido-pyrrolopyrazole 3 | 4-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair