BDBM121253 US8722896, (-)-(2R)-2-Methyl-3-(indol-7- ylmethylamino)-N-(3,4-dihydro- 2H-1,5-dioxepino-[2,3-b]pyridin- 8-ylmethyl)-N- isobutylpropanamide

SMILES CC(C)CN(Cc1cnc2OCCCOc2c1)C(=O)C(C)CNCc1cccc2cc[nH]c12

InChI Key InChIKey=KYEYCFUQJSHWMW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121253   

TargetProkineticin receptor 2(Cricetulus griseus (Chinese hamster))
The Regents Of The University Of California

US Patent
LigandPNGBDBM121253(US8722896, (-)-(2R)-2-Methyl-3-(indol-7- ylmethyla...)
Affinity DataKi:  1.39nM ΔG°:  -12.6kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents Of The University Of California

US Patent
LigandPNGBDBM121253(US8722896, (-)-(2R)-2-Methyl-3-(indol-7- ylmethyla...)
Affinity DataKi:  6.68nM ΔG°:  -11.6kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent