BDBM121358 US8722896, 3-Amino-N-(3,4-dihydro-2H- 1,5-benzodioxepin-7-ylmethyl)- N-isobutylpropanamide

SMILES: CC(C)CN(Cc1ccc2OCCCOc2c1)C(=O)CCN

InChI Key: InChIKey=SRYBLSFYSVYTPU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 2 (PRK2) (Cricetulus griseus (Chinese hamster))	BDBM121358 (US8722896, 3-Amino-N-(3,4-dihydro-2H- 1,5-benzodio...) Show SMILES CC(C)CN(Cc1ccc2OCCCOc2c1)C(=O)CCN Show InChI InChI=1S/C17H26N2O3/c1-13(2)11-19(17(20)6-7-18)12-14-4-5-15-16(10-14)22-9-3-8-21-15/h4-5,10,13H,3,6-9,11-12,18H2,1-2H3	UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-7.09	n/a	n/a	n/a	n/a	n/a	n/a	37
The Regents of the University of California US Patent					Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...				US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF
					More data for this Ligand-Target Pair