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BDBM121411 US8722709, 14

SMILES: Cc1ccc(cc1)-n1nccc1-c1ccnc(NC(N)=O)c1

InChI Key: InChIKey=FEAWMYRPBWYWEY-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121411   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM121411
PNG
(US8722709, 14)
Show SMILES Cc1ccc(cc1)-n1nccc1-c1ccnc(NC(N)=O)c1
Show InChI InChI=1S/C16H15N5O/c1-11-2-4-13(5-3-11)21-14(7-9-19-21)12-6-8-18-15(10-12)20-16(17)22/h2-10H,1H3,(H3,17,18,20,22)
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MMDB

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Similars

US Patent
n/an/a 14n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair