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BDBM121440 US8722709, 44

SMILES: NC(=O)Nc1cc(CCc2ccccc2C(F)(F)F)ccn1

InChI Key: InChIKey=FJYVFPUQYHIRKW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121440   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM121440
PNG
(US8722709, 44)
Show SMILES NC(=O)Nc1cc(CCc2ccccc2C(F)(F)F)ccn1
Show InChI InChI=1S/C15H14F3N3O/c16-15(17,18)12-4-2-1-3-11(12)6-5-10-7-8-20-13(9-10)21-14(19)22/h1-4,7-9H,5-6H2,(H3,19,20,21,22)
PDB
MMDB

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Similars

US Patent
n/an/a 13n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair