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BDBM121703 US8722692, 142

SMILES: Cn1cnc2cc(nc(OCc3ccccc3)c2c1=O)-c1ccc(nc1)C(C)(C)O

InChI Key: InChIKey=ZHHKMHWEEOPZIN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121703   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM121703
PNG
(US8722692, 142)
Show SMILES Cn1cnc2cc(nc(OCc3ccccc3)c2c1=O)-c1ccc(nc1)C(C)(C)O
Show InChI InChI=1S/C23H22N4O3/c1-23(2,29)19-10-9-16(12-24-19)17-11-18-20(22(28)27(3)14-25-18)21(26-17)30-13-15-7-5-4-6-8-15/h4-12,14,29H,13H2,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 181n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Compounds of the examples provided herein were assessed for their ability to inhibit Syk kinase by utilizing Caliper Life Sciences' proprietary L...


US Patent US8722692 (2014)


BindingDB Entry DOI: 10.7270/Q24Q7SNS
More data for this
Ligand-Target Pair