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BDBM121795 US8722692, 234

SMILES: COCCNCCc1ccc(cc1)-c1cc2ncn(C)c(=O)c2c(NC2CC2)n1

InChI Key: InChIKey=CNAVUPIXXMBOGM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121795   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM121795
PNG
(US8722692, 234)
Show SMILES COCCNCCc1ccc(cc1)-c1cc2ncn(C)c(=O)c2c(NC2CC2)n1
Show InChI InChI=1S/C22H27N5O2/c1-27-14-24-19-13-18(26-21(20(19)22(27)28)25-17-7-8-17)16-5-3-15(4-6-16)9-10-23-11-12-29-2/h3-6,13-14,17,23H,7-12H2,1-2H3,(H,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 156n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Compounds of the examples provided herein were assessed for their ability to inhibit Syk kinase by utilizing Caliper Life Sciences' proprietary L...


US Patent US8722692 (2014)


BindingDB Entry DOI: 10.7270/Q24Q7SNS
More data for this
Ligand-Target Pair