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BDBM122636 US8735386, I-106

SMILES: Cc1noc(C)c1Nc1ncc2CCc3nn(C)c(c3-c2n1)-c1ccccc1Cl

InChI Key: InChIKey=XJUPWIIYOUIUBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122636   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM122636
PNG
(US8735386, I-106)
Show SMILES Cc1noc(C)c1Nc1ncc2CCc3nn(C)c(c3-c2n1)-c1ccccc1Cl
Show InChI InChI=1S/C21H19ClN6O/c1-11-18(12(2)29-27-11)24-21-23-10-13-8-9-16-17(19(13)25-21)20(28(3)26-16)14-6-4-5-7-15(14)22/h4-7,10H,8-9H2,1-3H3,(H,23,24,25)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+3n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...


US Patent US8735386 (2014)


BindingDB Entry DOI: 10.7270/Q2C827Z0
More data for this
Ligand-Target Pair