BDBM12311 (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide::3-{[(1R,2S,5S)-3-[(2S)-2-[(tert-butylcarbamoyl)amino]-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2-yl]formamido}-4-cyclobutyl-2-oxobutanamide::BOCEPREVIR::SCH 503034::acs.jmedchem.1c00409_ST.355

SMILES: CC(C)(C)NC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(C)C)C(C)(C)C

InChI Key: InChIKey=LHHCSNFAOIFYRV-UHFFFAOYSA-N

Data: 4 KI  26 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 12311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1a (SARS-CoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chymotrypsin-like elastase family member 1 (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil elastase (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chymase (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.37E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin L2 (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin S (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Procathepsin L (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin F (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil elastase (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Plasminogen (Human)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-structural protein 4b (Hepacivirus hominis)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-structural protein 4b (Hepacivirus hominis)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-structural protein 4b (Hepacivirus hominis)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (Hepacivirus C)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (HCV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (HCV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		14	-10.9	n/a	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM12311 (SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair